临床分离的表皮葡萄球菌耐药性分析

Surveillance on drug resistance of Staphylococcus epidermidis isolated from clinic

目的了解重庆地区表皮葡萄球菌所致医院感染的耐药情况。方法对临床收集的42株表皮葡萄球菌进行药物敏感试验并分析结果。结果表皮葡萄球菌对米诺环素、利福平、阿米卡星、替考拉林的敏感性较高,敏感率均达到80%以上;对青霉素G,苯唑西林,红霉素的耐药性最严重,均在80%以上;无万古霉素耐药的表皮葡萄球菌;耐甲氧西林的表皮葡萄球菌(MRSE)检出率高达85.7%。结论表皮葡萄球菌的耐药情况严重,MRSE菌株的检出率高,应引起高度重视,临床治疗必须根据药敏试验结果选择合适的抗生素。

Objective To understand the antimicrobial resistance of Staphylococcus epidermidis causing nosocomial inl＇ections in Chongqing. Methods Among the 42 strains of Staphyloeoccus epidermidis isolated from clinic, antibiotics susceptibility test was used and the results were analysed. Results The sensitivity of Staphylococcus epldermidis to minoeycline, rifampin, amikacin, teieoplani was higher, and the rates all reached to 80%. The resistant rate to penicillin G and erythromycin was worst, all over 80%. none strains was resistant to vancomycln. The rate of meticillin-resistant Staphylococcus epidermidis（MRSE） was 85.7%. Conclusion The drug reaistance of Staphylococcus epldermidis is worse. It is important to reconstruct the rate of MRSE and choose the antimicrobial according antibiotics susceptibility test,