合成工艺对3-氯-2-羟基丙磺酸钠产率及时间的影响

Effect of synthesis technology on sodium 3-chloro-2-hydroxy propanesulfate yield and the time of reaction

以环氧氯丙烷和亚硫酸氢钠为原料合成3-氯-2-羟基丙磺酸钠,探讨了不同的加料顺序及原料的用量对产率的影响,并用红外光谱对产物的结构进行了表征。实验表明,环氧氯丙烷过量能使亚硫酸氢钠充分反应,有利于反应产物的提纯和产率的提高,产率为95.1%;而且使得反应时间有所缩短为2h。产物的熔点为253±1℃。

Sodium 3-chloro-2-hydroxy propanesulfate was synthesized from epichlorohydrin and sodium bisulfite . The effect of molar ratio of sodium bidulfite to epiehlorohydrin and the order of adding material on the yield was investigated . The highest yield is 05. 1%. The structure and component of the product was vertified by IR spectrum.