摘要
在过去的数十年中,大量的黄素依赖型单加氧酶被分离并研究。研究表明,黄素蛋白单加氧酶可以催化许多种类的氧化反应,如区域选择性羟基化反应和对映选择性磺化反应。这些氧化反应用常规的化学氧化剂难以或根本不能氧化。对已获得的基因组序列的分析表明,存在更多的黄素蛋白单加氧酶,并有待于在生物催化方面的作用进行进一步的研究。此外,经选择的一些黄素蛋白单加氧酶有突出的生物催化潜能。
During the last decades,a large number of flavin-de- pendent monooxygenases have been isolated and studied.This has revealed that flavoprotein monooxygenases are able to catalyze a re- markable wide variety of oxidative reactions such as regioselective hydroxylations and enantioselective sulfoxidations.These oxidation reactions are often difficult,if not impossible,to be achieved using chemical approaches.Analysis of the available genome sequences has indicated that many more flavoprotein monooxygenases are existed and the explorations biocatalytically are awaited.Furthermore,the biocatalytic potential of a selected number of flavoprotein monooxy- genases is highlighted.
出处
《化学工业与工程技术》
CAS
2006年第6期44-48,共5页
Journal of Chemical Industry & Engineering