嗜酸性粒细胞增多性脑膜炎28例临床分析

A clinical analysis on 28 cases with eosinophilic meningoencephalitis

对28例嗜酸性粒细胞增多性脑膜炎患者的临床特点及实验室、流行病学资料进行分析，结果显示，所有患者均有食生螺肉史，潜伏期2～20d；以剧烈头痛、躯体痛为主要临床表现，脑膜刺激征不明显；周围血及脑脊液中嗜酸性粒细胞明显增高；头颅CT正常，脑电图α波变慢；用阿苯哒唑、地塞米松治疗效果好，预后佳。

The clinical and laboratory data as well as the epidemiological information of 28 cases with eosinophilic meningoencephalitis were analyzed. The results indicated that ＂all the Patients had a history of eating raw fresh water snail, incubation period ranged from 2 to 20 days. The major symptoms of the patients were severe headache and pain in the trunk and limbs. Eosinophilia was noted in peripheral blood and cerebrospinal fluid. Electron cephalogram showed slow alpha rhythm. Albendazole and dexamethazone were effective for treatment of the patients.