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干细胞与感音神经性耳聋 被引量：1

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摘要 随着干细胞研究的深入,特别是近年来内耳干细胞的发现,为感音神经性耳聋的治疗带来了希望,本文就内耳干细胞的研究进展以及干细胞在感音神经性耳聋治疗的应用前景作一综述。
作者 江红群 王正敏 李华伟
机构地区 复旦大学附属眼耳鼻喉科医院耳鼻喉科
出处 《国际耳鼻咽喉头颈外科杂志》 2006年第6期357-359,共3页 International Journal of Otolaryngology-Head and Neck Surgery
关键词 干细胞(Stem Cells) 听觉丧失 感音神经性(Hearing Loss Sensorineural)
分类号 R764.43 [医药卫生—耳鼻咽喉科]
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参考文献16

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同被引文献21

  • 1Lawlor P, Marcotti W, Rivolta MN, et al. Differentiation of mammalian vestibular hair cells from conditionally immortal, postnatal supporting cells. J Neurosci, 1999, 19: 9445-9458.
  • 2Germiller JA, Smiley EC, Ellis AD, et al. Molecular characterization of conditionally immortalized cell lines derived from mouse early embryonic inner ear. Dev Dyn, 2004,231 : 815- 827.
  • 3Li H, Liu H, Heller S. Pluripotent stem cells from the adult mouse inner ear. Nat Med, 2003, 9: 1293-1299.
  • 4White PM, Doetzlhofer A, Lee YS, et al. Mammalian cochlear supporting ceils can divide and trans-differentiate into hair cells. Nature, 2006, 441: 984-987.
  • 5Doyle KL, Kazda A, Hort Y, et al. Differentiation of adult mouse olfactory precursor cells into hair cells in vitro. Stem Cells, 2007, 25 : 621-627.
  • 6Li H, Roblin G, Liu H, et al. Generation of hair cells by stepwise differentiation of embryonic stem cells. Proc Natl Acad Sci USA, 2003, 100: 13495-13500.
  • 7Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science, 1999, 284: 143-147.
  • 8Fang B, Shi M, Liao L, et al. Multiorgan engraftment and multilineage differentiation by human fetal bone marrow Flk1 +/ CD31-/CD34-Progenitors. J Hematother Stem Cell Res, 2003, 12 : 603-613.
  • 9Jeon S J, Oshima K, Heller S, et al. Bone marrow mesenchymal stem cells are progenitors in vitro for inner ear hair cells. Mol Cell Neurosci, 2007, 34: 59-68.
  • 10Safford KM, Safford SD, Gimble JM, et al. Characterization of neuronal/glial differentiation of murine adipose-derived adult stromal cells. Exp Neurol, 2004, 187: 319-328.

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国际耳鼻咽喉头颈外科杂志
2006年 第6期

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