硝酸铵催化的2,10-环氧蒎烷液相重排反应规律研究

Liquid-phase isomerization of 2,10-epoxypinane catalyzed by NH_4NO_3

研究了硝酸铵催化剂体系和溶剂对2,10-环氧蒎烷液相重排反应的影响.重点考察了催化剂分散状态、溶剂性质及溶剂用量对重排产物分布的影响.实验结果表明:用硅胶吸附的硝酸铵具有较好的活性,强极性的硝基甲烷溶剂中对于紫苏醇的选择性最好,而弱极性的氯仿和1,1,1-三氯乙烷则有利于桃金娘烯醇的生成.

The products distribution of liquid isomerization of 2,10-epoxypiane in the presence of NH4 NO3 was studied in this paper. The influences of different catalyst systems, solvents and the amount of solvent on the isomerization were investigated. It is discovered that perilly alcohol can be obtained in a high selectivity by NH4NO3 which is absorbed on silica gel in CH3NO2, but myrtenol was obtained as the main product catalyzed by NH4NO~ in CHCl3 and CCl3CH3.