8Thompson C B.Apoptosis in the pathogenesis and treatment of disease[J].Science,1995;267:1456-1462.
9Kato Y,Morikawa A,Sugiyama T et al.Role of tumor necrosis factor-alpha and glucocoticoid on lipopolysaccharide(LPS)-induced apoptosis of thymocytes[J].FEMS Immunol Med Microbiol,1995;12:195-204.
10Boland M P,Foster S J,O′Neill L A.Daunorubicin activates NF kappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cell[J].J Biol Chem,1997;272:12952-12960.
2[1]Zumsteg U, Frigerio S, Hollander GA. Nitric oxide production and Fas surface expression mediate two independent pathways of cytokine-induced murine β-cell damage. Diabetes,2000,49:39-47.
3[2]Liu CC, Young LHY, Young JD. Lymphocyte-mediated cytolysis and disease. N Engl J Med,1996,335:1651-1659.
4[3]O'Brien BA, Harmon Br, Cameron DP, et al. Apoptosis is the mode of β-cell death responsible for the development of IDDM in the nonobese diabetic(NOD) mouse. Diabetes,1997,46:750-757.
5[4]Nakata M, Uto N, Maruyama I,et al. Nitric oxide induces apoptosis via Ca2+-dependent processes in the pancreatic beta-cell line MIN6. Cell Struc Funct,1999,24:451-455.
6[5]Yamada K, Ichikawa F, Ishiyama-shigemoto S, et al. Essential role of caspase-3 in apoptosis of mouse β-cells transfected with human FAS. Diabetes,1999,48:478-483.
7[6]Shimabukuro M, Zhou YT, Levi M, et al. Fatty acid-induced β celll apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci USA,1998,95:2498-2502.
8[7]Maedler K, Spinas GA, Dyntar D, et al. Distinct effects of saturated and monounsaturated fatty acids on β-cell turnover and function. Diabetes,2001,50:69-76.
9[8]Grill V, Bjorklund A. Overstimulation and β-cell function. Diabetes,2001,50(Supppl.1):S122-124.
10[9]Donath MY, Gross DJ, Cerasi E, et al. Hyperglycemia-induced β-cell apoptosis in pancreatic islets of Psammomus Obesus during development of diabetes. Diabetes,1999,48:738-744.
7Schaberg DS, Norwood JM. Case study: infections in diabetes mellitus[J]. Diabetes Spectrum, 2002, 15:37-40.
8Mine S, Okada Y, Tanikawa T, et al. Increased expression levels of monocyte CCR2 and monocyte chemoattractant protein-1 in patients with diabetes mellitus [J]. Biochem Biophys Res Commun, 2006, 344(3): 780-785.
9Chipitsyna G, Gong Q, Gray CF, et al. Induction of monocyte chemoattractant protein-1 expression by angiotensin II in the pancreatic islets and beta-cells [J]. Endocrinology, 2007, 148 (5) : 2198-2208.
10Giulietti A, Overbergh L, Valckx D, et al. An overview of realtime quantitative PCR: applications to quantify cytokine gene expression [J]. Methods, 2001, 25(4): 386-401.
