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原发性胆汁性肝硬化患者血清中抗gp210抗体检测的临床意义 被引量：1

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摘要 目的探讨原发性胆汁性肝硬化(PBC)患者血清中抗gp210抗体检测的临床意义。方法采用酶联免疫吸附实验(ELISA)检测PBC,病毒性肝炎,结缔组织病和正常体检者血清中抗gp210抗体,并与其它几种相关自身抗体进行比较。结果抗gp210抗体在PBC患者组中阳性率为33.3%(18/54),而在病毒性肝炎,结缔组织病及正常体检组中均为阴性。抗gp210抗体阳性患者中肝功能衰竭的发生率明显高于抗gp210抗体阴性患者。结论抗gp210抗体不仅可以作为检测PBC的特异性指标,而且可以作为预后指标。
作者 谭爱国 高明 刘爱华
机构地区 卫生部北京医院检验科 卫生部北京医院风湿免疫科
出处 《中国医师杂志》 CAS 2006年第12期1692-1693,共2页 Journal of Chinese Physician
关键词 肝硬化 胆汁性 病毒包膜蛋白质类 抗体 抗核
分类号 R575.2 [医药卫生—消化系统]
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参考文献8

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中国医师杂志
2006年 第12期

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