基于Web的代谢网络仿真环境

Metabolic Network Simulation Environment Based on Web

针对实时服务的需求和大规模代谢网络的大计算量,构建了一个基于集群系统的多层体系结构的代谢网络仿真环境,主要采用Applet技术、系统生物学描述语言(SBML)、Servlet与Applet之间的通信技术、线程池技术和负载平衡机制来实现。基于这个仿真环境,结合已有的代谢网络仿真技术,提供了一个远程在线的代谢网络的仿真服务。该仿真环境不仅便于升级和维护,而且具有平台无关性、强大的计算性能和对重负荷的支持能力。

To the demand of real-time service and a great deal of computer by large-scale metabolic network,a metabolic network simulation environment of muti-layers framework based on cluster is constructed.Using Applet,SBML （Systems Biology Markup Language）,the communication between Servlet and Applet,thread pool and Load balancing,the environment is completed.Based the environment and technology of metabolic network simulation,the on-line service of simulation is provided.The framework is not only convenient to be maintained and upgraded,but also has the independent of platform,the strong computational ability and the sustainability to the heavy traffic.