La(Ⅲ)与β-丙氨酸缩β-萘酚醛双核配合物的合成、表征及其与DNA的作用

Synthesis and Characterization of La(Ⅲ) Binuclear Complex with 2-Hydroxy-1-Naphthaldehyde-β-Alanine and Its Interaction with DNA

合成了La(Ⅲ)与希夫碱β-丙氨酸缩β-萘酚醛(以KHL表示)双核配合物。通过元素分析,IR,UV,摩尔电导及热分析,确定配合物的组成为[La2(L)2(NO3)2].2C2H5OH。采用荧光光谱法对其与DNA的作用进行了初步研究,结果表明:随着配合物浓度的增加,对EB-DNA体系的荧光猝灭作用增强,配合物与DNA发生了类似于EB的较强的插入作用。

The binuclear complex of Schiff base C14 H12 NO3 K（KHL） derived from 2-hydroxy-l-naphthaldehyde and β-alanine with lanthanide nitrate was synthesized and characterized by elemental analysis, IR, UV, TG-DTA, and molar conductance analysis. The composition of the complex was [La2（L）2 （NO3）2] · 2C2H5OH. The interaction of the complex and DNA was studied by fluorescence spectrum. The result indicates that the La（ Ⅲ ） complex could cause a sharp decrease in the fluorescence intensity of EB-DNA system, and the complex could partly sustain the place of EB.