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肝细胞生长因子在心血管疾病诊断及治疗中的应用 被引量:5

Advances of Hepatocyte Growth Factor in Cardiology(review)
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摘要 肝细胞生长因子是一个多效的间充质因子,可以调节细胞的生长、运动和形态,具有促进血管生成,保护血管内皮、心肌细胞和抑制细胞凋亡及氧化应激等多重作用。本文就其与各种心血管疾病之间的关系做一综述。 Hepatocyte growth factor (HGF) is a mesenchyme-derived pleiotropic factor which regulates cell growth, cell motility, and morphogenesis of various types of ceils, and is thus considered a humoral mediator of epithelial-mesenchymal interactions responsible for angiogenesis, apoptosis and oxidative stress, etc. This article reviewed the relationships between HGF and cardiovascular diseases.
作者 李萍 杨庭树
出处 《中国康复理论与实践》 CSCD 2006年第11期966-967,共2页 Chinese Journal of Rehabilitation Theory and Practice
关键词 肝细胞生长因子 心肌细胞 内皮细胞 缺血性心脏病 动脉粥样硬化 高血压 心脏移植 心功能不全 综述 hepatocyte growth factor cadioeyte endotheliocyte ischemie heart disease atherosclerotie disease hypertension hearttransplantation cardiac insufficiency review
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  • 1Sato T,Yoshinouchi T,Sugimoto T,et al.Significance of hepatocyte growth factor measurement in patients with acute myocardial infarction[J].Cardiol,1998,32(2):77-82.
  • 2Sato T,Yoshinouchi T,Sakamoto T,et al.Hepatocyte growth factor (HGF):a new biochemical marker for acute myocardial infarction[J].Heart Vessels,1997,12:241-246.
  • 3Zhu Y,Hojo Y,Ikeda U,et al.Production of hepatocyte growth factor during acute myocardial infarction[J].Heart,2000,83(4):450-455.
  • 4Nakamura T,Mizuno S,Matsumoto K,et al.Myocardial protection from ischemia/reperfusion injury by endogenous and exogenous HGF[J].Clin Invest,2000,106:1511-1519.
  • 5Tomita N,Morishita R,Higaki J,et al.Novel molecular therapeutic approach to cardiovascular disease based on hepatocyte growth factor[J].Atheroscler Thromb,2000,7:1-7.
  • 6Ueda H,Sawa Y,Matsumoto K,et al.Gene transfection of hepatocyte growth factor attenuates reperfusion injury in the heart[J].Ann Thorac Surg,1999,67:1726-1731.
  • 7Funatsu T,Sawa Y,Ohtake S,et al.Therapeutic angiogenesis induced by myocardial injection of naked cDNA plasmid encoding hepatocyte growth factor in ischemic canine heart[J].Thorac Cardiovasc Surg,2002,124(6):1099-1105.
  • 8Yoshitomi Y,Kojima S,Umemoto T,et al.Serum hepatocyte growth factor in patients with peripheral arterial occlusive disease[J].Clin Endocrinol Metab,1999,84:2425-2428.
  • 9Morishita R,Nakamura S,Hayashi S,et al.Therapeutic angiogenesis induced by human recombinant hepatocyte growth factor in rabbit hind limb ischemia model as cytokine supplement therapy[J].Hypertension,1999,33:1379-1384.
  • 10Taniyama Y,Morishita R,Aoki M,et al.Therapeutic angiogenesis induced by human hepatocyte growth factor gene in rat and rabbit hindlimb ischemia models:preclinical study for treatment of peripheral arterial disease[J].Gene Ther,2001,8:181-189.

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