紫外分光光度法测定普卢利沙星片中主药的含量

Determination of Main Pharmaceutical Ingredient in Prulifloxacin Tablets by Ultraviolet Spectrophotometry

目的：建立以紫外分光光度法测定普卢利沙星片中主药含量的方法。方法：以0．1mol·L^-1盐酸溶液为溶剂，测定波长为274nm。结果：普卢利沙星检测浓度在1～10μg·mL^-1范围内线性关系良好（r=0．9999），平均回收率为100．0％（RSD=0．31％，n=9）。结论：本方法操作简便，检测结果准确。

OBJECTIVE： To establish an ultraviolet spectrophotometry for the determination of the principal agent in prulifloxacin tablets. METHODS： 0. 1mol · L^-1 hydrochloric acid solution was taken as dissolvent and the detection wavelength was 274nm. RESULTS： The linear range of prulifloxacin was 1-10μg · mL^-1（r = 0.999 9）, and the average recovery was 100,0% （RSD = 0.31%, n = 9）. CONCLUSION ： The method is simple and accurate.