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基因药物在临床上的最新应用与研发 被引量：2

Latest clinical application and development of gene medicine
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摘要 应用现代医学和分子药物学手段,即基因和细胞疗法,临床治疗被传统医疗视为难以攻克的病症又进入一个相对的活跃期。本文概述了近年来临床上肿瘤和神经疾病的基因治疗的实践与进展,对基因药物临床上的安全性和基因产物表达的时效性的探索以及临床基因药物研究在研发全新的抗癌病毒载体,给药途径的优化和与干细胞技术的结合提供新思路。 The clinical trials of gene and cell therapies for diseases, which are difficult to treat by current medical methods, at are an active stage. The novel clinical practice, progress of gene and cell therapy in cancer and nerve system disorder, the safety concerns and the gene express duration exploration are reviewed here. New strategy such as developing new cancer targeted vector, optimization of gene delivery route, and combination with stem cell technology are discussed.
作者 许瑞安 刁勇 谢海棠
机构地区 华侨大学分子药物学研究所 安徽省药物临床评价中心
出处 《中国临床药理学与治疗学》 CAS CSCD 2006年第10期1092-1097,共6页 Chinese Journal of Clinical Pharmacology and Therapeutics
关键词 基因 分子疗法 细胞疗法 临床治疗 gene molecular therapy cell therapy clinical trial
分类号 R969 [医药卫生—药理学]
  • 相关文献

参考文献17

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同被引文献25

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引证文献2

二级引证文献3

中国临床药理学与治疗学
2006年 第10期

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