乳腺癌保留乳房治疗81例疗效观察

Breast-conserving operation for breast cancer:a report of 81 cases

目的观察保留乳房治疗早期乳腺癌的疗效。方法81例Ⅰ、Ⅱ期原发性乳腺癌患者,行保留乳房手术加术后放射治疗和化疗,并与同期行改良根治术的92例早期乳腺癌进行对比研究。结果81例保留乳房治疗患者于术后1年进行外观效果评定,优良率为90.1%(73/81)。92例改良根治术患者,5例出现复发及远处转移。两个组的近期疗效差异无统计学意义,P=0.5273。结论早期乳腺癌保留乳房治疗的疗效与改良根治术基本相同,美容效果满意优于改良根治术,是一种值得推广的治疗方法。

OBJECTIVE： To evaluate the efficacy of breast-conserving operation for early-stage breast cancer. METHODS： Eighty-one patients （group A） with early stage （stage Ⅰ or Ⅱ） breast cancer were treated with breast-conserving surgery. Group A was compared with 92 contemporaneous patients （group B） who accepted modified radical mastectomy. Two groups were followed by irradiation, chemotherapy and endocrinotherapy. RESULTS： All cases were assessed on cosmetic result one year after operation, and the cosmetic result was good in 90. 1% （73/81）. Five cases of group B recurred and metastasized. There was no significant difference in recent effect between the two groups, P = 0. 527 3. CONCLUSIONS. Breast-conserving surgery of early stage breast cancer is similar to modified radical mastectomy, and it is deserved clinical application for early-stage breast cancer because of reliable curative effect and favorable cosmetic resuit. But the long-term results need more observation.