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c-erbB-2基因生物学特性研究进展 被引量：14

Development of the biological featares of C-erbB-2
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摘要 c-erbB-2是一种细胞来源的原癌基因,编码具有蛋白激酶活性的细胞膜糖蛋白。本文从c-erbB-2基因的生物学活性,激活作用机制以及对该基因扩增引起各种肿瘤的发生做了综述,并探讨了该基因在肿瘤诊断预测中的重要作用和应用前景。 C - erbB - 2 is a proto - oncogene of cell. The gene codes a kind of membrane glycoprotein which has the activity of tyrosine kinase. The biological features of c - erbB - 2 gene and its activation mechanism in tumor development was discussed. The amplification of c - erbB - 2 gene in different tumors was reviewed. The important prognostic and predictive value and application of c - erbB - 2 gene to patients with the tumor were explored.
作者 仇丽红 赵梅香 黄洁 高峰 洪义欢 陈建民
机构地区 扬州大学生物科学与技术学院
出处 《现代肿瘤医学》 CAS 2007年第1期102-105,共4页 Journal of Modern Oncology
关键词 C-ERBB-2 基因扩增 肿瘤 c - erbB - 2 gene amplification tumor
分类号 R730.231.3 [医药卫生—肿瘤]
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参考文献23

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二级参考文献53

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现代肿瘤医学
2007年 第1期

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