摘要
在N,N′-亚甲基二丙烯酰胺(Bis)存在的条件下,以偶氮二异丁腈(AIBN)为引发剂,使苯乙烯单封端聚乙二醇(St-PEG)大分子单体与丙烯酸(AAc)在3-戊酮溶液中进行分散共聚反应,得到了聚乙二醇-co-聚丙烯酸(PEG-co-PAAc)交联微球.动态激光光散射测试结果表明,所得的交联微球具有良好的单分散性;同时发现,在共聚反应中St-PEG大分子单体、AAc和Bis溶液浓度对交联微球粒径有明显的影响;交联微球的Rh在pH为4.5附近突然增加,并在pH>7.0后保持不变,说明该PEG-co-PAAc交联微球具有明显的pH响应性.
The pH-responsive crosslinking poly （ethylene glycol）-co-poly （acrylic acid） （PEG-co- PAAc） microspheres were prepared by dispersion copolymerization of St-PEG macromonorner with acrylic acid in 3-pentanone in the present of N, N＇-methylenehisacrylamide （Bis） as crosslinker and 2, 2＇-Azohis（isobutyronitrile） （AIBN） as initiator. The dynamic laser light scattering （DLS） measurement showed that the crosslinking microspheres have narrow size distribution. The effects of reaction parameters such as AAc concentration, PEG macromonomer concentration and Bis concentration on the Rh of obtained ctosslinking microspheres were investigated. It was also found that the PEG-co-PAAc crosslinking microspheres behave excellent pH-responsive and exhibit a rapid increase inRh when the pH value varies from about 4.5 to 7.0.
出处
《江南大学学报（自然科学版）》
CAS
2006年第6期730-733,共4页
Joural of Jiangnan University (Natural Science Edition)
基金
国家自然科学基金资助项目(50443012)
关键词
丙烯酸
聚乙二醇大分子单体
分散共聚
交联微球
PH响应性
acrylic acid
St-PEG macromonomer
dispersion copolymerization
crosslinking
microsphere
pH-responsive
