79颗患牙采用bFGF胶原膜盖髓的临床观察

Clinical observation of using collagen membrane with bFGF for the treatment of dental pulp capping

目的:探讨79例采用碱性生长因子(bFGF)的胶原蛋白膜盖髓的临床疗效,为临床寻找更有效的盖髓材料提供参考。方法:应用含有bFGF胶原蛋白膜对36颗因龋病和43颗因牙外伤而穿髓的患牙进行盖髓,分析其术后效果,同时与应用氢氧化钙对17颗因龋病和33颗因牙外伤而穿髓的患牙进行盖髓的疗效进行对比。结果:应用含bFGF胶原蛋白膜治疗外伤穿髓的盖髓效果优于氢氧化钙(P<0.05),应用含bFGF胶原蛋白膜治疗外伤穿髓的效果优于龋病治疗意外穿髓的效果(P<0.05),但含bFGF胶原蛋白膜与氢氧化钙比较,对龋病治疗意外穿髓的盖髓效果无显著性差别(P>0.05)。结论:含碱性生长因子的生物膜可以作为盖髓材料在临床应用。

Aim： To investigate the clinical efficacy of using collagen membrane with bFGF for the treatment of dental pulp capping in 79 cases, in order to find out more effective materials tocover the pulp. Methods： Thirty - six decayed teeth and 43 traumatic teeth combining with penetrating pulp were caped with collagen membrane with bFGF. Clinical outcomes were analyzed and compared with that of using calcium hydroxide to cover pulp in 17 decayed teeth and 33 traumatic teeth combining with penetrating pulp. Results： The efficacy of using collagen membrane with bFGF to cover pulp in traumatic teeth was better than that of using calcium hydroxide （P 〈 0.05 ）. The efficacy of using collagen membrane with bFGF for covering pulp in traumatic teeth was better than that in caries teeth. However,there was no significant difference between using collagen membrane with bFGF and using calcium hydroxide for pulp capping in the caries cases（ P 〉 0. 05 ）. Conclusion： The biological membrane with bFGF can be put into clinical application for covering the pulp.