早期鼻空肠肠内营养在重症急性胰腺炎治疗中的应用

Early enteral nutrition in the treatment of severe acute pancreatitis

目的探讨早期鼻空肠营养(earlyenteralnutrition,EEN)在重症急性胰腺炎(severeacutepancreatitis,SAP)治疗中应用的安全性和有效性。方法将我院2004年12月～2006年2月收治的47例SAP患者分为肠外营养(parenteralnutrition,PN)组和EEN组,观察住院天数、各种并发症、病死率、医疗费用的差异和APACHE-Ⅱ评分等,并将其治疗结果作对比。结果EEN组平均住院天数,二重感染均低于PN组,病死率下降,治疗总费用显著减少,APACHE-Ⅱ评分下降,与PN组比较有统计学意义。结论EEN在SAP中的应用是安全有效的,值得临床进一步推广。

Objective To evaluate the rational regimen of early enteral nutrition （EEN） in the treatment of severe acute panereatitis （SAP）. Methods In this prospective study 47 SAP patients were divided into EEN and parenteral nutrition （PN） groups. The length of stay, the incidence of serinus complications, mnrtality, curative effect, A- PACHE- Ⅱ grade and costs were compared between two groups. Results The mean length of stay, the rates of serious complications were significantly lower in the EEN group as compared with PN group. The APACHE- Ⅱ grade and the cost in EEN was markedly lower than in patients who recived PN. The mortality was dropped. Conclusion Early enteral nutrition is a safe and effective method used in seven Mute pancreatitis.