经(鼻)面罩双水平气道正压通气治疗慢性阻塞性肺疾病并Ⅱ型呼吸衰竭昏迷

Treatment of Stuporose Patients with COPD and Type Ⅱ Respiratory Failure by Noninvasive Bi-Level Positive Pressure Ventilation Via(nose)Face Mask

目的评价经(鼻)面罩双水平气道正压通气(BiPAP)治疗慢性阻塞性肺疾病(COPD)并Ⅱ型呼吸衰竭昏迷患者的疗效。方法应用(鼻)面罩BiPAP呼吸机对10例COPDⅡ型呼吸衰竭昏迷患者进行机械通气治疗,观察通气前后的临床表现及血气分析,并与8例行常规药物治疗的患者进行比较。结果无创通气组动脉血pH、PaCO2在通气后有明显改善(P<0.001),好转8例(8/10,80.0%),药物治疗组好转5例(5/8,62.5%),两组比较差异有显著意义(P<0.05)。结论经(鼻)面罩BiPAP通气治疗对COPDⅡ型呼吸衰竭昏迷患者有效,昏迷并不是经(鼻)面罩BiPAP通气的禁忌证。

Objective To evaluate the effect of Noninvasive Bi-level Positive Pressure Ventilation via （nose） Face Mask on Stuporose Patients with COPD and Type Ⅱ Respiratory Failure. Methods Ten stuporose patients with COPD and type Ⅱ respiratory failure were treated with Noninvasive Bi-level Positive Pressure Ventilation via （nose） Face Mask and 8 patients were treated with rule drugs. Results Arterial hood pH,PaCO2 of the Noninvasive ventilation group were improved obviously after the treatment of ventilation（P〈0.001）. Eight patients were improved in Noninvasive ventilation group （8/10,80.0 %） and 5 patients were improved in drugs group （5/ 8,62.5%）. There was significant change of two groups（P〈0. 05）. Conclusion Noninvasive Bilevel Positive Pressure Ventilation via（nose）Face Mask is effective for stuporose patients with COPD and type Ⅱ respiratory failure; Stupor is not the contraindication of Noninvasive Bi-level Positive Pressure Ventilation via（nose）Face Mask.