用于高强度聚焦超声热消融的PAA模块:模块的制作及声学参数的测量(英文)

PAA phantom for use in thermal ablation of high intensity focused ultrasound: Phantom fabrication and acoustic parameters measurements

目的研制一种透明的用于高强度聚焦超声热消融的PAA模块,并对其声学参数进行测量。方法观察模块浓度的不同所致颜色与透明度的变化,并对PAA模块的声学特性包括密度、声速及声衰减进行测量。结果(1)PAA模块为透明的琥珀色,蛋白浓度越高,颜色越深,透明度越低。(2)PAA模块的密度与水相近,为1.0250g/cm3至1.0617g/cm3。声速与模块浓度之间有明显的相关性。声衰减从0.125dB/cm至0.329dB/cm,随着模块密度与探头频率的增加而增加。结论PAA模块是一种较好的用于高强度聚焦超声热消融的均质仿体,实验结果有较好的重复性。

Objective An optically transparent phantom used for thermal ablation of HIFU has been developed with acoustic parameters measured. Methods The color and transparency of different concentration phantoms were observed. Properties including density, acoustic speed and acoustic attenuation of PAA gel phantom were measured. Results （1）PAA gel phantom was amber and transparent. The color became heavier and transparency decreased with the egg-white concentration increasing. （2）The density of PAA gel phantom was similar to water, which was from 1.0250g/cm3 to 1.0617g/cm3. There was a significant correlation between sound speed and phantom concentration. The acoustic attenuation was from O.125dB/cm to 0.329dB/cm, increased with the phantom density and transducer frequency increasing. Conclusions PAA gel phantom was homogeneous and a good mimicking phantom for HIFU thermal ablation. The experiment results had a satisfied reproducibility.