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ABC-AⅠ调节胆固醇跨细胞膜外向转运的研究进展 被引量：2

Progression of ABC-AⅠ regulating cholesterol transport through plasma membrane
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摘要 胆固醇跨细胞膜外向转运是胆固醇逆向转运过程(RCT)中具有关键意义的一步,三磷酸腺苷结合盒转运子家族AⅠ(ABCA-Ⅰ)在该过程中被公认为发挥十分重要的作用且对其研究至今仍然在不断深入。目前,大多数学者认为对其作用机制及与其他参与该过程的物质间相互作用的研究有可能成为防治动脉粥样硬化并促其转归的新突破口。 The cholesterol translocateing through the plama member is an important step in the reverse cholesterol efflux （RCT）. It is generally accepted that ATP-binding cassette transports-AⅠ（ ABC-AⅠ ） plays a very important role in studies of effecting mechanisms of ABC-AⅠ will probably become new breakthrough of this process. Nowadays most scholars believe that and its interaction between the others elements in more deeply that process atherosclerosis theory and promote its turnover. The recent review describes a series of achievements about the progression of ABC-AⅠ regulating cholesterol transport through plasma membrane.
作者 袁皓瑜 廖端芳
机构地区 湖南衡阳南华大学药物药理研究所
出处 《国际病理科学与临床杂志》 CAS 2006年第6期507-510,共4页 Journal of International Pathology and Clinical Medicine
关键词 三磷酸腺苷结合盒转运子AⅠ 动脉粥样硬化 胆固酵 调节 ABC-AⅠ atherosclerosis cholesterol regulation
分类号 R363 [医药卫生—病理学]
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参考文献22

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同被引文献42

  • 1张发艳,华声瑜,范英昌.丹酚酸B及丹参酮ⅡA对家兔动脉粥样硬化IL-8及VCAM-1的影响[J].山东中医药大学学报,2006,30(2):152-154. 被引量：28
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国际病理科学与临床杂志
2006年 第6期

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