脑小血管病变

Cerebral Small Vessel Disease

脑白质和中央灰质的小血管病变(SVD)是血管性痴呆的重要亚型,小血管病变痴呆的特点是认知障碍的功能障碍型,神经功能缺损包括失衡、失禁和情绪障碍。SVD在健康成人和轻度认知障碍患者中也比较常见,很容易被影像技术所显现,但难以与混合性SVD/AD相鉴别。文章就SVD的研究进展和有待解决的问题进行综述。

Small vessel disease（SVD）of the cerebral white and central grey matter is an important subtype of vascular dementia （VD）.SVD-dementia is characterized by a dysexecutive type of cognitive impairment,neurological deficits including imbalance and voiding dysfunction ,and emotional disturbances ,SVD is also frequent among clinically healthy subjects and patients with mild cognitive impairment,It is easily visualized by imaging techniques,but difficult to distinguish from mixed SVD/Alzheimer Disease ,This article reviews the recent progress in research on SVD and the problems have to be resolved.