ABO血型与幽门螺旋菌感染关系及其意义

ASSOCIATION OF ABO BLOOD GROUP WITH HELICOBACTER PYLORI INFECTION AND ITS SIGNIFICANCE

本文采用细菌学和血清学方法检测了２１７例胃、十二指肠疾病患者和１６９例健康输血员幽门螺旋菌（ＨｅｌｉｃｏｂａｃｔｅｒｐｙｌｏｒｉＨＰ）感染情况和ＡＢＯ血型，以探讨ＨＰ感染与ＡＢＯ血型系统之间的关系。结果表明：消化性溃疡各组患者Ｏ型血所占的比例均较高；胃十二指肠疾病患者和健康输血员中Ｏ型血人群ＨＰ阳性率分别为８９．５８％和５１．７８％，显著高于其它血型（Ｐ＜０．００５、０．０５）；并且在同一疾病中ＨＰ阳性者Ｏ型血所占的比例显著高于ＨＰ阴性者（Ｐ＜０．０２５）。提示：Ｏ型血人群对ＨＰ易感染，这可能是Ｏ型血患者胃粘膜上皮细胞表面较非Ｏ型血人群有更多的ＨＰ受体所致。

The Helicobacler pylori and ABO blood group of 217 patients and 169 blood donorswere identified by bacteriologic and serologic method,Aiming to expore the relation between H. pylori infection and ABO blood group. The result show: (1) Among patients with peptic ulcer there were a increase in the proportion of blood group O; (2) The infection rate of H.pylori in the proportion of bloodgroup O was significatly higher than in those not blood group O (P< 0. 005, 0. 05) ;(3) In same kind dis ease the rate of blood group O was significatly higher in patients with H.pylori positive than in thosewith H. pylori negative. The result suggested: The proportion of blood group O were susceptible to H.pylori, Maybe there were more receptors of H. pylori on the epithelial cells in stomach in proportion ofblood group O.