摘要
目的:介绍国外治疗深部真菌病药物两性霉素B新剂型在临床的应用。方法:主要进入全球权威的临床医学文献数据库美国国立医学图书馆(NLN)的Mediline数据库,检索了近10年来有关两性霉素B新剂型在临床应用的大量文献,概括地进行综述和分析。结果及结论:国外临床应用的两性霉素B的剂型有10余种,并且很多剂型已经收入各国药典之中,而国内目前仅有3种,建议尽快开发各种新剂型,以满足临床各方面的需求。
OBJECTIVE：To introduce the overseas clinical application of new dosage forms of amphotericin B in the treatment of deep mycosis. METHODS： We reviewed literatures and analyzed the data about the clinical application of new dosage forms of amphotericin B over the past 10 years by retrieving the global authoritative mediline database - the USA national medicine library （NLN）. RESULTS ＆ CONCLUSION： More than 10 dosage forms of amphotericin B are being used abroad, and many of which have been recorded in pharmacopeia of each country. However, only 3 dosage forms are being used in China, therefore, it is suggested that new dosage forms should be developed as early as possible to satisfy the clinical demands.
出处
《中国医院用药评价与分析》
2006年第6期339-341,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
两性霉素B
临床应用
剂型
amphotericin B
clinical application
dosage form
