医院空气中细菌与临床感染的关系研究

STUDY OF RELATIONSHIP BETWEEN THE BACTERIA IN AIR AND THE CLINIC INFECTION

医院感染已列为国家质量管理的一个重要组成部分,感染菌的来源,主要分内源性菌,即患者自身带的菌又感染了自己。另一种是外源性菌,即外环境包括空气中的细菌、各种物品中的细菌、人员接触等。医院内感染;以呼吸道感染占首位(59％),空气传播是引起感染的重要方面,空气中病原性微生物的污染程度直接决定感染率的高低。为了弄清医院空气中菌群分布情况及从空气中和临床患者中分离出同一类菌的关系,进行了对比实验及耐药性分析,现将结果报告如下。

The source of infectious bacteria is the first problem in provension of infection considered by the medical workers. In this paper, with the method of bacteria plasmid analysis, chromosome DNA restriction fragment length polymorphism analysis, drug resistance experiment (antibacterial drug, sterilizing drug) and so on. We confirmed that staphylococci of nosocomi is mainly fromair; but the gram-negative bacteriais mainly from the patient's pharyngeal portionp; and cause hospital infection indirectly. The drug resistance of gram-negative from air was lower than the same gram-negative bacilli's isolated from the patient. Moreever, kill bacteria the infectious strain is same strain in air. Above-mentioed results provided the important basis for control of the hoslpital infection.