冠状动脉钙化与冠心病的相关性分析

A correlation analysis on coronary artery colcification and coronary heart disease

目的:探讨冠状动脉钙化(CAC)与冠心病(CHD)的相关关系及钙化对CHD的诊断价值。方法:对433例CHD患者(CHD组)和158例非CHD患者(非CHD组)做冠状动脉造影并详细记录相关临床指标,对两组患者的CAC、冠状动脉狭窄情况进行比较分析。结果:年龄和脂蛋白a(LPa)与CAC呈正相关。CHD组有226例(52.19%)检出钙化,CAC多见于左前降支近段(172段)、左前降支中段(77段)、左回旋支近段(46段)。非CHD组有32例(20.25%)检出钙化,CAC多见于左前降支近段(20段)、左前降支中段(10段)。CHD组与非CHD组钙化范围不同(P<0.01),程度不同(P<0.01)。结论:CAC的危险因素为年龄、LPa,CAC与CHD的危险因素并不完全相同。CHD患者较正常人有更高的CAC检出率。CAC与冠状动脉狭窄在病变部位、范围、程度上有一定的相关性,但并不完全相同。

Objective： To investigate the relationship between coronary, artery calcification （CAC） and stenosis and on the value of CAC for diagnosing coronary artery disease （CHD）. Methods： Clinical data of 433 patients with CHD and 158 patients with none CHD were recorded and examined by selective coronary angiography. The correlation between calcification and stenosis were assessed, compared and analyzed in two groups. Results： Age and lipoprotein（a） were risk factors of CAC. In CHD group, the CAC rate was 52.19%. There was often occurred CAC in LAD proximal segment （172）, LAD middle segment （77）, LCX proximal segment （46） in these patients. However, in non-CHD group, the CAC rate was 20.25%. There was often occurred CAC in LAD proximal segment （20）, LAD middle segment （10）, in non-CHD patients. The two groups patients were different in CAC range and degree. Conclusions： The CAC risk factors were age and lipoprotein（a）. The risk factors were different between CAC and stenosis. In lesion＇s site, range and degree, CAC and stenosis had some correlation.