冠心病病人室早发生与心率变化临床分析

The clinical analysis between the occurrence of ventricular premature beat and the heart rate change among coronary heart disease(CHD)

目的：分析冠心病和非冠心病病人室性早搏发生规律及机制。方法：选择109例住院患者，根据冠状动脉造影的结果分为冠心病组（53例）和非冠心病组（56例），依据动态心电图检查结果，做单位小时平均心率和室早发生百分率或干分率随24h时间变化曲线，观察两曲线变化情况，并对两组进行对比分析。结果：非冠心病组两曲线多呈一致，且室早发生率峰值在第一个平均心率峰值出现的同时或其后；冠心病组两曲线多呈相反或无关，室早发生率峰值在第一个平均心率峰值之前（约夜间1～7时）。结论：非冠心病病人室早发生可能与交感神经兴奋增强、迷走神经张力降低有关，冠心病病人室早发生恰与此相反。

Objective： To analyse the occurrence rate of ventricular premature beat between coronary heart disease（CHD） and non-CHD. Methods： We have collected 109 patients and divided them into CHD group （53 patients） and non-CHD group （56 patients） by coronary angiography. We maked the curve of two groups by the results of 24 hours ECG and compared these curves. Results： Two curves of non-CHD group were at the same trend but those of CHD group are not at the same trend. Most ventricular premature beat of CHD group occured at 1 to 7 AM. Conclusions： The occurrence of ventricular premature beat of non- CHD is related with more tensive sympathetic nerve and less tensive vagus, but which of CHD is reverse.