重型颅脑损伤患者开颅术后医院感染及其危险因素分析

Postoperative nosocomial infection and its risk factors in severe craniocerebral injury

目的:了解重型颅脑损伤患者开颅术后医院感染的危险因素,探讨医院感染的预防和控制措施。方法:采用单因素方差分析和多因素L og istic回归对215例重型颅脑损伤手术患者的医院感染资料进行分析。结果:重型颅脑损伤术后患者的医院感染率为33.0%;危险因素依次为年龄、留置胃管、抗生素联合应用、手术时间、脑室引流时间、住院时间。结论:年龄、留置胃管、抗生素联合应用、手术时间、脑室引流时间、住院时间是重型颅脑损伤患者开颅术后医院感染发生的危险因素。

Objectlve： To explore the risk factors and their preventive measures for postoperative nosocomial infection （NI） in severe craniocerebral injury. Methods： Clinical data of 215 patients with severe craniocerebral injury undergoing craniotomy in our hospital were analyzed. Results ： The postoperative NI rate was 33%. The risk factors were age, retained gastric tube, combined use of antibiotics, operative time, ventricular drainage time, and hospital stay. Conclusion： The above-mentioned six factors are closely related to the development of NI in patients with severe craniocerebral injury.