摘要
以戊二醛为交联剂、Fe3O4为磁核，采用反相悬浮交联技术合成了磁性壳聚糖微球，并利用数码光学显微成像仪、激光粒度仪、傅立叶红外光谱对磁性微球的形态、大小和化学结构进行了表征，采用原子吸收分光光度仪、磁天平和可调磁场对其磁响应性进行了研究．结果表明：所合成的磁性壳聚糖微球粒径在50～200μm之间，基本呈圆球形，表面比较光滑，且内部均匀分布着磁性介质Fe2O4；当磁性微球粒径小于280μm时，在外加磁场作用下，微球的磁化率与沉降速度都随着微球粒径的增大而增大．这表明所制备的磁性壳聚糖微球具有良好的磁响应性．
Magnetic chitosan microspheres were synthesized by means of the reverse-phase suspension cross-linking technique, with glutaraldehyde as the cross-linker and Fe3O4 as the magnetic core. The morphology, and chemical structure of the prepared microspheres were then characterized using the digital optical particle size microscope,the laser granularity meter and the FTIR, and the magnetic resonance of the microspheres was investigated using the atom-absorbing spectrophotometer, the magnetic balance and the adjustable magnetic field. The results demonstrate that the prepared magnetic chitosan microspheres are well-shaped spheres with a diameter from 50 to 200 μm, in which Fe3O4 particles disperse uniformly, and that, when the microspheres in an external magnetic field are of a diameter of less than 280 μm, its magnetic susceptibility and sedimentation rate increase with the size. It is indicated that the prepared magnetic chitosan microspheres are of excellent magnetic resonance.
出处
《华南理工大学学报（自然科学版）》
EI
CAS
CSCD
北大核心
2006年第12期92-95,100,共5页
Journal of South China University of Technology(Natural Science Edition)
基金
国家自然科学基金资助项目(20306007)
高等学校博士学科点专项科研基金资助项目(20050561014)
广东省自然科学基金重点项目(04105934)
关键词
磁核
磁响应性
磁化率
沉降
magnetic cores
magnetic resonance
magnetic susceptibility
sedimentation
