Vasculogenic Mimicry and Its Molecules Signaling Pathways

Tumors require a blood supply for growth and hematogenous metastases. Until recently, most research in this field has focused on the role of angiogenesis, the recruitment of new vessels into a tumor from preexisting vessels. The term vasculogenic mimicry describes the formation of fluid-conducting channels by highly invasive and genetically dysregulated tumor cells. Vasculogenic mimicry provides an opportunity to investigate the interrelationships between the genetically dysregulated invasive tumor cell, the microenvironment, and the malignant switch. This article is purposed to present the models and the molecule mechanisms of tumor vasculogenic mimicry.

Tumors require a blood supply for growth and hematogenous metastases. Until recently, mast research in this field has focused on the role of angiogenesis, the recruitment of new yes,As into a tumor from preexisting vessels. The warn vaseulogenic mimicry describes the formation of fluld-condueting channels by highly invasive and genetically dysregulated tumor cells. Vaseulogenie mimicry provides an opportunity to investigate the interrelationships between the genetically dysregulated invasive tumor cell, the microenvironment, and the malignant switch. This artide is purposed to present the models and the molecule mechanisms of tumor vasculogenie mimicry.