摘要
目的探讨肺结核的耐药性特点。方法对我院2004年9月～2006年9月期间就诊的肺结核患者51例的药物敏感性结果进行回顾性分析。结果肺结核患者初始耐药性为20.0%,继发耐药率为90.5%,总耐药率为49.0%;初始祖耐多药率为3.3%,复治组为19.0%,总耐多药率为9.8%。结论近年来肺结核患者耐药率较高,应重视对抗结核药物的耐药性监测,以便了解耐药趋势;并应加强肺结核患者的管理,合理用药以减少耐药的发生。
Objective To analyse the resistance of anti-tuberculosis drugs in patients with pulmonary tuberculosis. Methods Rstrospectively investigate the drug susceptibility testing （DST） results of patients with pulmonary tuberculosis.from sep.2004 to sep, 2006. Results The initial drug resistance rate was 20.0%,acquired drug resistance rate was 90.5%,total drug resistance rate was 49.0%;the multi-drug resistance was 3.3%,19.0% respectively for newly diagnosis patients and retreatment patients,the total muhdrug resistance rate was 9.8%. Conclusion The drug resistance rate of anti-TBdrug resistance with pulmonary tuberculosis very high in recent years,the surverv of anti-TB drug resistance and the management of TB should be imnosed.
关键词
肺结核
药物治疗
耐药性
pulmonary tuberculosis
Drug susceptibility testing （DST）
resistance of anti-TB
