血脂异常与蒙古族高血压关系

Relationship between hyperlipemia and hypertension in Mongolian people

目的研究血脂异常与蒙古族高血压的关联性。方法对2547名20岁～蒙古族居民进行血压等的测量，吸烟、饮酒等因素的调查及血脂的检测，采用单因素χ^2及多因素非条件Logistic回归分析进行统计分析，以OR值作为评价关联的指标，Mantel-Haenszelχ^2趋势检验法分析甘油三酯（TG）与高血压间的剂量．反应关系。结果单因素分析结果显示，总胆固醇（TC）异常、甘油三酯（TG）异常、低密度脂蛋白胆固醇（LDL-C）异常与高血压相关联（P〈0．001）。经Logistic回归模型分析，调整了年龄、性别、体质指数（BMI）、腰臀比（WHR）、血糖和高血压家族史等因素后，TC异常及LDL-C异常与高血压的关联差异无统计学意义（P〉0．05）。而TG异常与高血压之间的关联差异仍有统计学意义（OR=1．579，95％CI=1．232-2．024）。剂量．反应关系分析结果显示，蒙古族高血压的患病危险性有随着TG的升高而增高的趋势。结论TG异常可能是蒙古族高血压的独立危险因素。高血压的患病危险有随TG水平升高而增高的趋势。

Objective To investigate correlation between hyperlipemia and hypertension in Mongolian people. Methods The blood pressure and so on were measured and factors including smoking eigarette and alcohol intake, and blood lipids for 2 547 Mongolian people aged 20 and elder were investigated, the statistic analysis were done by using chi square test and multiple logistic model, and correlations were evaluated by using odd ratio（ OR ）, dose-effect relations between TG and hypertesion were analyzed by means of Mantel-Haenszel chi square trend test. Results Single factor analysis showed that high total eholesterol（TG）, high triglyceride（TG）, high low density lipoprotein-cholesterol（LDL-c） were all correlated with hypertension. After adjustment for age, gender, body mass index（BMI）, waist-hip ratio（WHR）, blood glucose and family history of hypertension by multiple logistic model, there were no correlations between high TC, high LDL-c and hypertension（ P 〉0.05）. There were still a significant correlation between high TG and hypertension（ （ OR 1.579, 95 % CI 1. 232 - 2.024）. Results of dose-effect analysis showed that the risk of prevalence for hypertension increased with TG level. Conclusion High TG may be a independent risk factor of hypertension in Mongolian people, and there was a tendency that the risk of prevalence of hypertension increased with TG level.