C-反应蛋白水平与脑梗死病情及预后的相关关系

Relationships between serum C-reactive protein levels and severity of cerebral infarction

目的 探讨脑梗死患者血清C-反应蛋白水平与病情严重程度及预后的相关关系。方法 测定92例病程7d内的脑梗死患者入院当时和治疗2wk后血清CRP含量，观察脑梗死灶不同面积含量变化，并对其神经功能缺损进行标准评分。同时选取96例健康体检人员血清CRP含量进行对照。结果 （1）脑梗死患者血清CRP含量明显高于健康对照组（P〈0．05）；（2）脑梗死患者血清CRP含量变化与梗死灶大小及神经功能缺损程度关系密切。结论 CRP水平是临床评价脑梗死严重程度和预后的一个重要的生物学指标。

Objective To investigate the relationships between serum C-reactive protein levels and severity of cerebral infarction. Methods The serum CRP and NSE levels of 92 cerebral infarction patients who were observed at two different time were measured： one within 7 days and the other in 2 weeks later. The 96 normal people was used as control group. Results （1） The levels of CRP in cerebral infarction patients were markedly higher than that of control group （P〈0.05）. （2） There was an obvious corelationships between the size of infarct and the level of CRP and NSE. Conclusion CRP can be a sensitive markers of the patients with cerebral infarction.