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唇腭裂相关基因的研究进展 被引量:3

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摘要 唇腭裂是人类出生缺陷的重要组成部分.需要外科、营养、牙科、语言、内科和行为等各学科的介入,给社会和家庭带来重大的经济负担。唇腭裂的发病率随着地理位置和社会经济发展程度的不同而不同,有一定差异性,平均是1/700。大体上,亚洲或美国印地安人有最高的发病率,1/500或更高.高加索人居中.非洲人最低1/2500。唇腭裂病因学的复杂性为鉴定基圜和基困一环境之间相互作用提供了很大的机遇,也可以更多更深的认识人体胚胎学与其相关疾病。
作者 胡浪 仇小强
出处 《现代预防医学》 CAS 北大核心 2007年第1期55-57,共3页 Modern Preventive Medicine
关键词 唇腭裂
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参考文献29

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同被引文献55

  • 1杨如镜,刘安民,李洪玲,任芬若,黄鸿恩,张,韩书心.洛阳鹤壁两地区唇腭裂调查及遗传分析[J].河南医学研究,1995,4(3):219-221. 被引量:3
  • 2万伟东,王丽君,周小平,周德兰,章庆国,黄金龙,王小宁.MTHFR基因C677T和A1298C多态与中国部分人群非综合征性唇腭裂的相关研究[J].中华整形外科杂志,2006,22(1):8-11. 被引量:32
  • 3史晓泓,唐慧,梁怡.新生儿唇腭裂畸形的致病因素研究进展[J].中国妇幼保健,2006,21(7):1006-1007. 被引量:24
  • 4张芳真,郑苍尚.先天性唇腭裂病因研究进展[J].深圳中西医结合杂志,2007,17(2):122-125. 被引量:3
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