摘要
[目的]了解口服重组B亚单位/菌体霍乱菌苗(肠溶胶囊)在服用后的不良反应,为其推广应用提供科学依据。[方法]选择北京市朝阳、丰台两个区,抽取412人全程口服重组B亚单位/菌体霍乱菌苗,观察服药后的副作用。[结果]没有严重副作用发生,服药后的副作用均为一过性的腹痛、腹泻、头晕等,总副作用发生率6.55%,客观副反应发生率为0.73%,总副反应的发生存在地区聚集性,故不能排除心因性反应的可能。[结论]口服重组B亚单位/菌体霍乱菌苗(肠溶胶囊)副作用发生率低,无严重副反应发生,可以考虑在适当人群中推广应用。
[ ObjectiVes] To observe the side effects of oral cholera vaccine, provide evidence for applying and popularizing this vaccine [ Methods] 412 people of 2 districts 0f Chaoyang and Fengtai in Beijing were selected as sample. The side effects were observed after they took the oral cholera vaccine. [ Results] All of the side effects after taking the oral cholera vaccine were templel such as bellyache, diarrhea and dizziness, The rate of all kinds of side effects was 6.55% and that of the impersonal side effects was 0.73%. Psychogenic reaction couldn＇t be excluded because of the aggregation of total side effects. [Conclusions] Because the rate of side effects of oral cholera vaccine is low and no severe side effects have happened, the oral cholera vaccine can be popularized in proper people.
出处
《现代预防医学》
CAS
北大核心
2007年第1期128-130,共3页
Modern Preventive Medicine
关键词
口服霍乱菌苗
安全性
心因性
Oral Cholera Vaccine
Safety
Psychogenic reaction
