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血管紧张素Ⅱ受体1型阻滞剂与胰岛素抵抗的关系 被引量：4

The Relationship Between Angiotenson Ⅱ Subtype 1 Receptor Blockers and Insulin Resistance
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摘要 血管紧张素Ⅱ受体1型阻滞剂(ARBs)对心、脑、肾等靶器官的降压外保护作用已为越来越多的基础研究和临床试验所支持并因此得到广泛的应用。现就肾素-血管紧张素系统(RAS)与胰岛素抵抗(IR)的相互关系及作为RAS阻滞剂的ARBs的代谢效应在改善IR相关疾病中的作用及可能机制作一系统的复习。 The protective effects of angiotenson Ⅱ subtype 1 receptor blockers （ ARBs） on their end-organs, such as the heart, brain and kidney, have been demonstrated by many basic experiments and clinical trials. These effects appeared to be potentially independent of their effect of lowering blood pressure. Application of ARBs has become widespread. This article describes the relationship between the renin-angiotcnsin system and insulin resistance and the application of the metabolic effects of ARBs in order to improve insulin resistance in concerned diseases.
作者 陈远刚 陈明
机构地区 重庆医科大学附属第一医院心内科
出处 《心血管病学进展》 CAS 2007年第1期96-99,共4页 Advances in Cardiovascular Diseases
关键词 血管紧张素Ⅱ受体1型阻滞剂 胰岛素抵抗 代谢效应 angiotenson Ⅱ subtype 1 receptor blockers insulin resistance metabolic effect
分类号 R587 [医药卫生—内分泌]
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参考文献30

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心血管病学进展
2007年 第1期

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