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中药止咳汤剂对急性气管炎患者血清中白三烯C_4和血小板活化因子的影响 被引量:3

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摘要 目的探讨中药止咳汤剂治疗急性气管炎所致阵发性痉挛性咳嗽的疗效以及拮抗患者血清中白三烯C4(LTc4)和血小板活化因子(PAF)等炎症介质的作用。方法将50例急性气管炎以阵发性痉挛性咳嗽为主诉的患者随机分为两组。A组22例用中药汤剂治疗,B组28例采用西药常规治疗,14天为一疗程。两组治疗前后进行症状评分和留取血清标本检测LTc4和PAF比值,同时设空白对照组。结果A组症状积分由25.29±4.09降至4.67±1.46,LTc4和PAF比值显著降低,接近空白对照组。B组症状积分由19.32±2.11降至7.04±1.07,LTc4和PAF比值也有明显改善,但仍高于A组和空白对照组。A与B组间差值的比较有显著差异(P<0.01)。结论中药止咳汤剂不仅能改善急性气管炎的症状,而且拮抗气道炎症介质LTc4和PAF的作用也明显优于西药组。
出处 《中国临床医生杂志》 2007年第1期50-52,共3页 Chinese Journal For Clinicians
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