肝病患者凝血象和红细胞参数检测的临床意义

Clinical significance of coagulation parameters,platelet parameters and erythrocyte parameters in hepatopathy patients

目的了解肝病患者凝血象和红细胞参数的变化,并探讨其临床意义。方法对85例肝病患者进行凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、凝血酶时间(TT)、纤维蛋白原(FIB)四项凝血指标测定,并同时进行平均红细胞体积(MCV)、红细胞体积分布宽度(RDW)和血小板计数(PLT)的检测。结果85例肝病患者测定结果表明,PT、TT、APTT均较对照组明显延长(P＜0．05),除肝癌外,FIB均较对照组明显减低(P＜0．05)。除急黄肝MCV与对照组差异无显著性外,其他各项差异均有显著性(P＜0．05)。结论肝病患者血液患者血液处于明显的低凝状态,提示及时对肝病患者进行凝血因子的检测,有利于预防继发性出血,指导临床治疗,避免并发症的发生。

Objective To analyze clinical significance of coagulation parameters, platelet parameters and erythocyte parameters in occurrence of hepatopathy patients. Methods Prothrombin time（PT）, activated partial thromboplastin time（APTT）, thrombin time（TT）, fibrinngen（FIB） and mean corpuscular volume（MCV）, RBC distribution width（RDW）, bleed platelet count（BPC） in 85 bepatopathy patients were determined. Results The PT, APTr, Tr in 85 cases of hepatopathy patients were longer than those in the control group （P 〈 0.05） and the value of FIB were reduced except in the hepatic carcinoma ptients （ P 〈 0.05）. There was significant difference in the value of MCV, RDW, BPC between the patients and control group except the value of MCV in severe icteric hepatits patients （P 〈 0.05）. Conclusion The coagulation parameters in hepatopathy patients were in a state of low cosgulation, suggesting that the determination of coagulation parameters, phatelet parameters and erythrocyte parameters is helpful for preventing secondary bleeding and complications as well as guiding clinical treatment.