氮芥类烷化剂的检测和药代动力学研究
The detection and pharmacokinetics of cyclophosphamide and oxazaphsphorines
摘要
氮芥类烷化剂是临床上常用的抗肿瘤药物，直到今天，问世40多年来磷杂环蟋烷类化合物环磷酰胺仍被广泛用于临床，其也是多种多组分化疗药物处方中的一员。最常用的两种磷杂环曙烷类药物为环磷酰胺和异磷酰胺，另外还有氯乙环磷酰胺和马磷酰胺。本文将重点对生物样品中磷杂环烷类抗肿瘤药物的检测方法，及其在体内的药物动力学性质进行综述。
出处
《中国热带医学》
CAS
2007年第1期124-125,共2页
China Tropical Medicine
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