α-溴-2,5-二甲氧基苯乙酮的合成

Synthesis of 2-Bromo-1-(2,5-dimethoxyphenyl)ethanone

通过甲醇体系中利用溴化氢溴代α一氯2,5-二甲氧基苯乙酮的方法,获得了α-溴一2,5-二甲氧基苯乙酮,进一步和苯甲酸反应得到了苯甲酸-(2,5二甲氧基苯羰甲基)酯。研究表明该化合物在非极性溶剂苯中,没有光化学活性。在具有氢给体能力的甲醇溶剂中,也没有观察到任何光化学变化。

2 -Bromo- 1 - （2,5 -dimethoxyphenyl）ethanone was synthesized by virtue of the reaction of halogen - exchange with higher yields. The further esterification proved that it is an effective chemical protective group. But no photolytic phenomena were observed whether in the H - donated solvent MeOH or in the Nonpolar solvent Benzene.