摘要
对浙江兰溪地区58例麻风治愈者及其27名直系亲属血清中的可溶性白细胞介素—2受体(SIL—2R)水平进行了研究,并以当地正常人作对照。发现PB治愈者的SIL—2R与对照者无差异(P>0.005),MB治愈者的则明显降低(P<0.002),以LL治愈者最显著(P<0.005),且与病程和治愈时间无关,提示MB病人治愈后仍有细胞因子异常和T细胞激活方面的障碍。麻风病人直系亲属的血清中SIL—2R明显高于MB治愈者(P<0.001),与PB治愈者和对照者无差异(P>0.05)。
soluble interleukin - 2 receptor (SIL - 2R) was determined in 58 persons cured of leprosy and 27 members of their families in Lanxi prefecture,Zhejiang, taking 28 local healthy residents as controls. The results showed that level of SIL-2R in persons who had MB leprosy, especially LL, was lower than in those who had PB leprosy and controls (P<0. 002) ,and had nothing to do with the disease duration and time to have been cured. The contents of SIL-2R in the members of the ex-patients' families were the same as in the controls (P>0. 05).
