摘要
目的:建立注射用头孢西丁钠的HPLC含量测定方法。方法:BonChrom·C_(18)柱(150mm×4．6mm,5μm);流动相为水-乙腈-冰醋酸(810:190:10);检测波长254nm;流速为1ml·min^(-1)。结果:头孢西丁在75～1200μg·ml^(-1)浓度范围内线性关系良好;平均回收率为100．0%,RSD0．1%。结论:本法简便、快速、准确。
Objective： To establish a HPLC method for determination the content of cefoxitin sodium for injection. Method. The Bon chrom C is column （ 150 mm × 4.6 mm,5 μm） was used. The mobile phase consisted of water-acetonitrile-glacial acetic acid （810 ： 190： 10）, the flow rate was 1ml·min^-1 ; the detection wavelength was at 254 nm. Result： The cefoxitin sodium presented a good linear correlation within arrange of 75 - 1200 μg·ml^-1, r = 0.999 9. The average recovery was 100.0%, RSD = 0.1%. Conclusion： This mothed is simple, rapid and accurate.
出处
《中国药师》
CAS
2007年第1期46-47,共2页
China Pharmacist
