高频通气体外膈肌起搏治疗慢阻肺和Ⅱ型呼吸衰竭附82例疗效观察

AN OBSERVATION ON THE EFFECT OF EXTERNAL DIApHRAGM PACING USING HIGH FREQUENCY VENTILATION FOR TREATING 82 CASES OF COPD AND TYPE Ⅱ RESPIRATORY FAILURE

60例慢性阻塞性肺病(简称慢阻肺)患者,经体外隔肌起搏治疗后,临床症状改善,膈肌动度增加,肺通气功能改善 PaO_2上升,PaCO_2下降,均有统计学差异,指出体外膈肌起搏是慢阻肺功能康复的简便有效的治疗方法。22例慢阻肺所致Ⅱ型呼衰患者,经高频通气配合体外隔肌起搏治疗,PaO_2迅速上升,PaCO_2下降,提示该疗法在Ⅱ型呼衰病情危害时使用利于防止因严重缺 O_2而损害心、脑、肝肾等重要器官导致多器官功能衰竭的危险,同时又可防止 PaCO)2过高而抑制其自主呼吸。

After the treatment with external diaphragm pacing,the clinical syndrome of 60 chronic obstructive pulmonary diseas(COPD)patients got better,the activation of di- aphragmatic muscle increased,the ventilation function of pulmones improved,P.O_2 rose,and P_aCO_2 decreased.All these have statistical differences,indicating that external diaphragm pacing is a simple and effective method for recovering COPD patients' pulmonary function. After the treatment with high frequency ventilation and external diaphragm pacing,the 22 cases of type Ⅱ respiratory failure patients caused by COPD showed P_aO_2 rising quickly and P_aCO_2 then decreased,it indicates this method can prevent the danger of MOF resulted from severe shortage of O_2 in heart,brain,liver,kidneys and other important organs in the time when patient's condition gets worse ,and it can also prevent the inhibition to auto-respiration by too high P_aCO_2.