冠心病患者血清脂蛋白(a)浓度变化

VARYING OF SERUM LIPOPROTEIN(a)CONCENTRATION IN SUBJECTS WITH CHD

检测了62例不同伴发病的冠心病患者及30例正常对照组的血清脂蛋白(a)浓度及其他血清脂质。结果显示:血清脂蛋白(a)的浓度,冠心病组显著高于正常对照组(P<0.01);冠心病组中三个不同伴发病亚组之间脂蛋白(a)浓度无显著差异(P<0.05)。一元线性回归分析显示 Lp(a)与TG,LDL-c 中度相关,与 TC 微弱相关、本文提示血清 Lp(a)浓度检测对 CHD 诊断有一定的参考价值。

In this study serum lipoprotein(a)[Lp(a)]and other lipid concentrations of 62 cases of coronary heart disease(CHD)and 30 controls were measured.The mean serum Lp (a)concentration of CHD group was much higher than those of controls(P<0.001).No dif- ferences in Lp(a)concentration between 3 subgroups of CHD can be observed.Linear Re- gression Analysis(LRA)showes that Lipoprotein(a)midlingly related with TG LDL-C, While wearly related with TC.Quantitating of serum Lp(a)has referential value in diagnosis for CHD.