1[1]O' Dowd BF,Heiber M,Chan A,et al.A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11.Gene,1993,136:355-360.
2[2]Tatemoto K,Hosoya M,Habata Y,et al.Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor.Biochem Biophys Res Commun,1998,251:471-476.
3[3]Hosoya M,Kawamata Y,Fukusumi S,et al.Molecular and functional characteristics of APJ.Tissue distribution of mRNA and interaction with the endogenous ligand apelin.J Biol Chem,2000,275:21061-21067.
4[4]Szokodi I,Tavi P,F(o)ldes G,et al.Apelin,the novel endogenous ligand of the orphan receptor APJ,regulates cardiac contractility.Circ Res,2002,91:434-440.
5[5]Berry MF,Pirolli TJ,Jayasankar V,et al.Apelin has in vivo inotropic effects onnormal and failing hearts.Circulation,2004,110(Suppl Ⅱ):S187-S193.
6[6]Foldes G,Horkay F,Szokodi I,et al.Circulating and cardiac levels of apelin,the novel ligand of the orphan receptor APJ,in patients with heart failure.Biochem Biophys Res Commun,2003,308:480-485.
7[7]Ishida J,Hashimoto T,Hashimoto Y,et al.Regulatory roles for APJ,a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo.J Biol Chem,2004,279:26274-26279.
8[8]Chen MM,Ashley EA,Deng DXF,et al.Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction.Circulation,2003,108:1432-1439.
7Scholtyssek H, Damerau W, Wessel R, et al. Antioxidative activity of ginkgolides against superoxide in an aprotic environment [ J ]. Chem Biol Interact, 1997,106 ( 3 ) : 183-190.
8Ash Euan ley, Powers J, Chen M, et al. The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo[ J]. Cardiovasc Res,2005, 65( 1 ) :73-82.
9Rona G,Chappe C I,Balazs T,et al. An infarct like myocardial lesion and other toxic manifestations produced by isoproterenol in the rat [ J ]. Arch Pathol, 1959,67 (4) : 443-455.
10Tatemoto K, Hosoya M, Habata Y ,et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor [ J ]. Biochem Biophys Res Commun, 1998,251 (2) :471-476.