1993－1994年南京地区病原真菌分析

Analysis of pathogenic fungi in Nanjing area from 1993 to 1994

目的目的探讨９０年代致病真菌的分布及动态变化．方法将患者标本接种于含氯霉素的葡萄糖蛋白胨琼脂培养基（ｃＳＡＢ）或含氯霉素及放线菌酮的葡萄糖蛋白胨琼脂培养基（ａｃＳＡＢ）上，置２５℃一２７℃温箱孵育．根据菌落特征、镜下结果鉴定其菌种，分类统计后与８０年代结果比较分析．结果分离的３８１株致病真菌中，红色毛癣菌居首位，须癣毛癣菌次之，再次为孢子丝菌；深部真菌病明显上升，浅部真菌病，尤其是头癣菌菌相有了较大变化．结论真菌病发病率上升．一些抗真菌药的广泛应用及其对敏感致病真菌的抑制作用，导致耐药菌株相对增多，使致病真菌菌相发生变化．

Objective To meearch the distribution anddynamic alteration of Pathogenic fungi after gds'..Metals The spehans from PatientSwas inoculated on culture medium of cSAB oracSAB in calefactor of 25t ￣ 27 t. The fungoustype was identify according to the characteristicof the colony and the resultS under gyroscope.The results was counted statistically according tothe microscopic class ification and compared withthe resultS of 80s'.Results Of the 381 strains of fungi isolated,T. rubrum was the most. The next was T.mentagrophytes. And the thick wasSPOrotrichum.The incidence of deep fungal infeCtion ascended obviously.The fungous type of thesuperficial mycosis, espeCially the Pathogenic fungiof tinea capitis, changed obvinusly.Concluhon The mycosis rate was rising.The extensive applying of some fungistatic drubsand their inhibihng to the sensitive fungi resultedin the increasing of the fungous type Which haveresistance to fungistatic drugS,and in the changeSof fungi picture.