复发性卵巢癌再次手术意义的探讨

Discussion on repeatoperation for recurrent ovarian carcinoma

目的探讨复发性卵巢癌再次行肿瘤细胞减灭术的临床效果。方法对我院及北京大学肿瘤医院1990年1月至2004年2月收治的68例复发性卵巢癌再次手术患者的临床资料进行回顾性分析。结果68例再次手术中,无肉眼残留26例,残留<2cm者18例,残留>2cm者24例,带瘤生存10例,无瘤生存11例,死亡47例。中位生存期手术组与非手术组无显著性差异。结论对于复发性卵巢癌,有条件者应选择再次手术,可以改善患者的一般状况,提高生活质量。

Objective The patients with recurrent ovarian carcinoma are usually associated with very complicated conditions, very difficult to treat, and the survival rate is very low. This paper explores the final outcome of repeat operations and cytoreduction operation for these patients. Methods The clinical data of 68 patients with recurrent ovarian carcinoma from January 1990 to February 2004 in People＇s Hospital, Peking University and Cancer Hospital Peking University were retrospectively analyzed. Results Among 68 cases with repeat operation no residual tumors could be observed grossly in 26 cases, residual tumors 〈 2 cm in 18 cases and residual tumors 〉 2 cm in 24 casess. Eleven cases survived with residual tumors, while other 47 cases died. There was no difference between median survival time and repeat operation. Conduslons For the recurrent ovarian carcinoma, repeat operation can improve patients＇ general condition and their guality of life.