老年高血压动态脉压及指数与尿白蛋白关系探讨

Correlation Between Dynamic Pulse Pressure,Pulse Pressure Index and Albuminuria in Senile Hypertensive Patients

目的:探讨老年高血压患者动态收缩压(SBP)、舒张压(DBP)、脉压(PP)和脉压指数(PPl)与尿白蛋白(A lD)的关系,评价脉压和脉压指数反映高血压早期肾损伤的价值。方法:使用动态血压监测仪分为4组,测量220例老年高血压患者的PP和PPI;采用免疫比浊法测定尿ALB和血脂的水平。结果:组间性别、年龄、血脂异常均无显著差异;脉压和脉压指数的增加,尿ALB水平明显增高(P<0.05)。结论:脉压和脉压指数与尿ALB水平密切相关,在评定高血压患者早期肾损伤方面价值比高。

Objective： To investigate the correlation of systolic blood pressure （ SBP ）, diastolic blood pressure（DBP） ,pulsepressure（PP） ,pulsepressure index（PPI） with albuminuria （ ALB）, to evaluate the value of PP and PPI in reflecting early renal injury. Method： 220 cases, whose PP and PPI level were measured by the dynamic blood pressure （BP） monitor and divided into 4 groups. ALB and blood lipid were determined by immune turbidimetric assay and the ALB level was compared among the groups. Result：Sex , age and the abnormal blood lipid were not significantly different among the groups. With the increase of PP and PPI, ALB level increased significantly （ P 〈0. 05）. Conclusion： There is close correlation between PP, PPI and ALB and they are more Valuable than SBP and DBP in reflecting early renal injury in hypertensive patients.