失眠患者多导睡眠图特点及药物治疗

Varieties of polysomnography in patients with insomnia and effects of medicines

目的探讨失眠患者多导睡眠图特点及药物治疗效果。方法对16例抑郁障碍相关性失眠患者给予美抒玉治疗2个月,13例焦虑障碍相关性失眠患者及10例特发性失眠患者给予思诺思治疗2个月,治疗前后行多导睡眠图及精神量表测定。另选15例健康查体者作为对照组。结果经美抒玉治疗后,抑郁障碍相关性失眠组总睡眠时间、慢波睡眠时间显著延长,睡眠效率提高,觉醒次数减少,抑郁自评量表改善。经思诺思治疗后,焦虑障碍相关性失眠组总睡眠时间延长,睡眠效率提高,睡眠潜伏期缩短,觉醒次数减少;特发性失眠组多导睡眠图未见异常,治疗后主观症状改善。结论失眠是一种主观感觉,多导睡眠图能对各种原因失眠的诊断提供帮助。

[Objective] To explore the varieties of polysomnography in patients with insomnia and to assess the effects of medicines. [Methods] 16 insomnia patients with depression were cared with trazodone, 13 insomnia patients with anxiety and 15 idiopathic insomnia patients were eared with zopidem. Polysomnography and rating scales for mental health were examined before and after medicine cares. [Results] After tfazodone cared, total sleep time, sleep efficiency index, NREM slow-wave sleep of insomnia patients with depression were significantly longer, while wake after ssleep onset was obvious lower, and self-rating depression scale was better. After zopidem cared, total sleep time and sleep efficiency index of insomnia patients with anxiety were significant longer, while sleep latency and wake after sleep onset were Obvious rlower. Polysomnography showed no statistical difference it idiopathic insomnia, patientS,r But after zopidem cared, it induced significant changes in subjective sleep and awakening quality. [Conclusions] Insomnia is subjective feeling. Polysomnography can help ascertain sorts of insomnia.