期刊文献+

argR基因对钝齿棒杆菌发酵过程中产精氨酸特性的影响 被引量:1

Effect of argR Gene on the Characteristic of Arginine Production in the Fermentation Process of Corynebacterium crenatum
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摘要 本文测定了一株钝齿棒杆菌(Corynebacteriumcrenatum)诱变菌和二株基因工程菌发酵过程中产arginine曲线、生长曲线以及发酵液中碳源消耗量和pH值的变化。实验结果显示Arg产量最高的菌株为C.crenatumA.S.M2.sp,其产量达到9mg/ml,据此认为钝齿棒杆菌中的argR基因可能为Arg代谢中的一个正调控因子。 In this paper, the growth curve and utility rate of carbon, the pruducing curve of arginine and the pH of the culture medium of C.crenatum were determined. The results showed that C.crenatumA.S.M2.sp is the bacterium which has the highest yield of arginene. The yield of this bacterium gets to 9mg/ml. In conclusion, argR gene of C.crenatum is a positive regulator in the metabolism of arginine.
出处 《食品科学》 EI CAS CSCD 北大核心 2006年第12期37-40,共4页 Food Science
基金 教育部长江学者和创新团队发展计划资助项目(IRT0540)
关键词 C.crenatumA.S.M2 C.crenatumA.S.M2△argR C.crenatumA.S.M2.sp Arg argR基因 C.crenatumA.S.M2 C.crenatumA.S.M2 △argR C.crenatumA.S.M2.sp Argl argR gene
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参考文献11

  • 1胡圣望,胡旺平,胡松林.中脑导水管周围灰质微量注射N-硝基左旋精氨酸和硝普钠对大鼠血压的影响[J].解剖学研究,2002,24(1):43-45. 被引量:5
  • 2Adrian Barbul,郭长江.精氨酸:生物化学、生理学及治疗学意义[J].氨基酸和生物资源,1987,15(2):39-43. 被引量:22
  • 3Kiyoshi Nakayama,et al.Fermentative production of L-arginine[J].Agric Biol Chen,1972,36(10):1675-1684.
  • 4Hajime Yoshida,et al.Mechanism of L-arginine production by L-arginine producing mutants of corynebacterium glutamicum[J].Agric Biol Chem,1979,43(1):105-111.
  • 5王霞,许正宏,敖宗华,孙志浩,陶文沂.L-精氨酸产生菌的选育及其发酵条件[J].药物生物技术,2001,8(4):210-212. 被引量:9
  • 6Alexandros K,Kiupakis,Larry Reitzer.ArgR-independent induction and ArgR-dependent superinduction of the astCADBE operon in Escherichia coli[J].Bacteriology,2002.184:2940-2950.
  • 7Anahit Ghochikyan,Iovka Miltcheva Karaivanova,Michèle Lecocq,et al.Arginine operator binding by heterologous and chimeric ArgR repressors from Escherichia coli and Bacillus stearothermophilus[J].Bacteriology,2002,184:6602-6614.
  • 8Takayuki Nishijyo,Seung-Moon Park,Chung-Dar Lu,et al.Molecular characterization and regulation of an operon encoding a system for transport of arginine and ornithine and the ArgR regulatory protein in Pseudomonas aeruginosa[J].Bacteriology,1998,180:5559-5566.
  • 9Lu C D,Yang Z,Li W,et al.Transcriptome analysis of the ArgR regulon in Pseudomonas aeruginosa[J].J Bacteriol,2004,186(12):3855-3861.
  • 10窦文芳,许正宏,陶文沂.碳源及添加模式对钝齿棒杆菌JDN28-75发酵生产L-精氨酸的影响[J].中国医药工业杂志,2004,35(5):272-274. 被引量:6

二级参考文献17

  • 1龚建华 等.L-精氨酸发酵条件的研究[J].微生物学报,1988,28(3):257-264.
  • 2龚建华,微生物学报,1988年,28卷,3期,257页
  • 3路志强,微生物学报,1988年,28卷,2期,131页
  • 4Barbul A,氨基酸杂志,1987年,2卷,39页
  • 5北京师范大学生物系生化教研室,基础生物化学实验,1982年
  • 6龚健华.L—精氨酸生产菌诱变育种的研究[J].微生物学报,1988,28(2):131-135.
  • 7Szende B, Tyihank E, Trezl L.Role of arginine and its methylated derivatives in cancer biology and treatment[J].Cancer Cell lnt, 2001, (1): 3-19.
  • 8Nakayama K, Yoshida H.Fermentative production of Larginine [J].Agric Biol Chem, 1972, 36 (4): 675-1684.
  • 9张龙翔.生物化学实验技术[M].北京:高等教育出版社,1989.27-29.
  • 10T. A. Lovick,B. J. Key. Inhibitory effect of nitric oxide on neuronal activity in the periaqueductal grey matter of the rat[J] 1996,Experimental Brain Research(3):382~388

共引文献41

同被引文献20

  • 1陈雪岚,许正宏,陶文沂.钝齿棒杆菌产精氨酸关键酶分析[J].食品科学,2005,26(3):35-39. 被引量:7
  • 2钱和,郝刚.L-精氨酸产生菌诱变育种的研究[J].微生物学通报,2005,32(3):46-50. 被引量:14
  • 3黄继红,王新春,王华南,赵俊平.L-精氨酸高产菌株的选育[J].氨基酸和生物资源,2005,27(3):46-48. 被引量:8
  • 4赵俊平,黄继红,和晶亮,王新春,王华南.N^+注入L-精氨酸产生菌诱变育种的研究[J].发酵科技通讯,2006,35(2):3-5. 被引量:3
  • 5Tan B,Yin Y,Liu Z,et al.Dietary L-arginine supplementation increases muscle gain and reduces body fat mass in growingfinishingpigs[J].Amino Acids,2009,37(1):169-175.
  • 6Ma X,Lin Y C,Jiang Z Y,et al.Dietary arginine supplementation enhances antioxidative capacity and improves meat quality of finishing pigs[J].Amino Acids,2008,35(4):651-659.
  • 720种氨基酸需求前景[N].中国产业信息网,2009.
  • 8Lu C D.Pathways and regulation of bacterial arginine metabolism and perspectives for obtaining arginine overproducing strains[J].Appl Microbiol Biotechnol,2006,70(3):261-272.
  • 9Shi D,Morizono H,Yu X,et al.Crystal structure of N-acetylornithine transcarbamylase from Xanthomonas campestris:a novel enzyme in a new arginine biosynthetic pathway found in several eubacteria[J].Biolog Chem,2005,280(15):14366-14369.
  • 10Xu Y,Labedan B,Glansdorff N.Surprising arginme biosynthesis:a reappraisal of the enzymology and evolution of the pathway in mlcroorgamsms[J].Microbiol Molecu BioL 2007,71(1):36-47.

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